Patient

Clinical Trial Finder β€” 12 Recruiting Trials for My Condition in 30 Seconds

12 recruiting trials found in 30 secondsHealth & Medical3 min read

Key Takeaway

The Medical Research Toolkit queries ClinicalTrials.gov to find actively recruiting studies matching your condition, location, and eligibility criteria. Stop scrolling through 50,000 trials β€” your agent finds the relevant ones in seconds.

The Problem

ClinicalTrials.gov has over 470,000 registered studies. Finding the right trial is like finding a needle in a haystack:

  • Search is primitive (keyword-based, no intelligence)
  • Results include completed, withdrawn, and terminated studies
  • Eligibility criteria are buried in dense text
  • Location filtering is clunky
  • No synthesis β€” just a list of 200+ results

For patients with rare or hard-to-treat conditions, clinical trials represent hope. But the barriers to finding and understanding trials keep most patients from ever enrolling. Only 5-8% of eligible patients participate in clinical trials.

The Solution

Your agent queries ClinicalTrials.gov through the Medical Research Toolkit, filters for actively recruiting studies, cross-references with literature, and presents a curated list with plain-language eligibility summaries.

The Process

View details
You: Find clinical trials recruiting for treatment-
resistant depression in adults. I'm in Paris, France.
Preferably novel mechanisms (not more SSRIs).

The agent queries and filters:

View details
## Active Clinical Trials β€” Treatment-Resistant Depression

Filters: Recruiting | Adults 18-65 | Europe/France |
Novel mechanisms (excluding SSRI/SNRI monotherapy)

### Top Matches (12 found)

1. 🟒 PSILOCYBIN-ASSISTED THERAPY
   NCT05XXXXXX | Phase 2b | COMPASS Pathways
   Location: HΓ΄pital Sainte-Anne, Paris
   Mechanism: 5-HT2A agonist (psychedelic-assisted)
   Status: Recruiting (18/120 enrolled)
   Key criteria: 2+ failed antidepressant trials,
   MADRS β‰₯ 20, no psychotic features
   Duration: 12 weeks + 6-month follow-up
   Compensation: Travel reimbursement
   Contact: dr.martin@sainte-anne.fr

2. 🟒 ESKETAMINE NASAL SPRAY (Extended Study)
   NCT05XXXXXX | Phase 3b | Janssen
   Location: PitiΓ©-SalpΓͺtriΓ¨re, Paris
   Mechanism: NMDA receptor antagonist
   Status: Recruiting (45/200 enrolled)
   Key criteria: Failed β‰₯2 adequate antidepressant
   trials in current episode
   Duration: 52 weeks
   Compensation: Yes (per visit)

3. 🟒 TRANSCRANIAL MAGNETIC STIMULATION (Stanford
   Accelerated Protocol)
   NCT05XXXXXX | Phase 2 | Multi-site
   Location: Institut du Cerveau, Paris
   Mechanism: Non-invasive neuromodulation
   Status: Recruiting
   Key criteria: HAMD-17 β‰₯ 17, medication-stable β‰₯4 weeks
   Duration: 5 days treatment + 4 weeks follow-up

[...9 more trials with similar detail]

### Summary Table
| Trial | Mechanism | Phase | Sites in France | Est. Completion |
|-------|-----------|-------|-----------------|-----------------|
| Psilocybin | 5-HT2A | 2b | 3 | 2027-Q2 |
| Esketamine | NMDA | 3b | 8 | 2027-Q4 |
| TMS Stanford | Neurostim | 2 | 2 | 2026-Q4 |
...

### My Assessment
The psilocybin trial at Sainte-Anne is the most novel
and has Paris availability. The Stanford TMS protocol
is the fastest (5 days). Esketamine has the most
existing efficacy data but is Phase 3b (extension).

Want me to draft an inquiry email to any of these sites?

The Results

MetricManual SearchAI Agent
Time2-4 hours30 seconds
Results relevanceMixed (lots of noise)Pre-filtered
Eligibility explainedDense medical textPlain language
Location filteringClunkyPrecise
Novel mechanism filterManual readingAutomatic
Next step supportNoneDraft inquiry email

Setup on MrChief

yamlShow code
skills:
  - medical-research-toolkit
  - doctor  # For eligibility interpretation
clinical-trialsClinicalTrials-govpatient-recruitmentdrug-development

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Clinical Trial Finder β€” 12 Recruiting Trials for My Condition in 30 Seconds β€” Mr.Chief