Patient
Clinical Trial Finder — 12 Recruiting Trials for My Condition in 30 Seconds
Key Takeaway
The Medical Research Toolkit queries ClinicalTrials.gov to find actively recruiting studies matching your condition, location, and eligibility criteria. Stop scrolling through 50,000 trials — your agent finds the relevant ones in seconds.
The Problem
ClinicalTrials.gov has over 470,000 registered studies. Finding the right trial is like finding a needle in a haystack:
- Search is primitive (keyword-based, no intelligence)
- Results include completed, withdrawn, and terminated studies
- Eligibility criteria are buried in dense text
- Location filtering is clunky
- No synthesis — just a list of 200+ results
For patients with rare or hard-to-treat conditions, clinical trials represent hope. But the barriers to finding and understanding trials keep most patients from ever enrolling. Only 5-8% of eligible patients participate in clinical trials.
The Solution
Your agent queries ClinicalTrials.gov through the Medical Research Toolkit, filters for actively recruiting studies, cross-references with literature, and presents a curated list with plain-language eligibility summaries.
The Process
View details
You: Find clinical trials recruiting for treatment-
resistant depression in adults. I'm in Paris, France.
Preferably novel mechanisms (not more SSRIs).
The agent queries and filters:
View details
## Active Clinical Trials — Treatment-Resistant Depression
Filters: Recruiting | Adults 18-65 | Europe/France |
Novel mechanisms (excluding SSRI/SNRI monotherapy)
### Top Matches (12 found)
1. 🟢 PSILOCYBIN-ASSISTED THERAPY
NCT05XXXXXX | Phase 2b | COMPASS Pathways
Location: Hôpital Sainte-Anne, Paris
Mechanism: 5-HT2A agonist (psychedelic-assisted)
Status: Recruiting (18/120 enrolled)
Key criteria: 2+ failed antidepressant trials,
MADRS ≥ 20, no psychotic features
Duration: 12 weeks + 6-month follow-up
Compensation: Travel reimbursement
Contact: dr.martin@sainte-anne.fr
2. 🟢 ESKETAMINE NASAL SPRAY (Extended Study)
NCT05XXXXXX | Phase 3b | Janssen
Location: Pitié-Salpêtrière, Paris
Mechanism: NMDA receptor antagonist
Status: Recruiting (45/200 enrolled)
Key criteria: Failed ≥2 adequate antidepressant
trials in current episode
Duration: 52 weeks
Compensation: Yes (per visit)
3. 🟢 TRANSCRANIAL MAGNETIC STIMULATION (Stanford
Accelerated Protocol)
NCT05XXXXXX | Phase 2 | Multi-site
Location: Institut du Cerveau, Paris
Mechanism: Non-invasive neuromodulation
Status: Recruiting
Key criteria: HAMD-17 ≥ 17, medication-stable ≥4 weeks
Duration: 5 days treatment + 4 weeks follow-up
[...9 more trials with similar detail]
### Summary Table
| Trial | Mechanism | Phase | Sites in France | Est. Completion |
|-------|-----------|-------|-----------------|-----------------|
| Psilocybin | 5-HT2A | 2b | 3 | 2027-Q2 |
| Esketamine | NMDA | 3b | 8 | 2027-Q4 |
| TMS Stanford | Neurostim | 2 | 2 | 2026-Q4 |
...
### My Assessment
The psilocybin trial at Sainte-Anne is the most novel
and has Paris availability. The Stanford TMS protocol
is the fastest (5 days). Esketamine has the most
existing efficacy data but is Phase 3b (extension).
Want me to draft an inquiry email to any of these sites?
The Results
| Metric | Manual Search | AI Agent |
|---|---|---|
| Time | 2-4 hours | 30 seconds |
| Results relevance | Mixed (lots of noise) | Pre-filtered |
| Eligibility explained | Dense medical text | Plain language |
| Location filtering | Clunky | Precise |
| Novel mechanism filter | Manual reading | Automatic |
| Next step support | None | Draft inquiry email |
Setup on MrChief
yamlShow code
skills:
- medical-research-toolkit
- doctor # For eligibility interpretation
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